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Apr 3, 2020 · Development of novel approaches requires a reproducible preclinical model of calcified CTO. CTOs were created in 18 femoral arteries of 9 New Zealand White rabbits using …
Feb 15, 2021 · Development of novel approaches requires a reproducible preclinical model of calcified CTO. Methods: CTOs were created in 18 femoral arteries of 9 New Zealand White …
Sep 1, 2009 · No reproducible animal model simulating human CTOs has previously been developed. We hypothesized that an apatite‐coated bioabsorbable polymer sponge could be …
Conclusions: This calcified model simulates occlusions found in humans CTO and will serve as a basic model for learning the pathophysiology of CTO calcification and development of treatments …
Jan 1, 2012 · This protocol describes a novel chronic total occlusion (CTO) model that features cell-mediated calcium deposits in rabbit femoral arteries. CTO is the most severe case of …
Sep 1, 2009 · This study demonstrates the potential of implanting a PCL-HOB construct in an animal artery to establish a model of atherosclerotic occlusion with calcification.
May 1, 2019 · We review the prevalence of spontaneous collaterals in different species, as well as review the current literature with respect to animal models of CTOs, and compare and contrast …
Summary Chronic total coronary occlusion (CTO) remains a major problem for percutaneous revascularization, with relatively low primary success rates and a high incidence of restenosis …
Sep 1, 2009 · No reproducible animal model simulating human CTOs has previously been developed. We hypothesized that an apatite-coated bioabsorbable polymer sponge could be …
We could successfully create a reliable and repeatable porcine coronary model of calcified total occlusions. This method can be utilized in many preclinical evaluations of CTO technologies.
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